A phenylpropanoid with antifungal and antioxidant activity
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Isomer(s)
31398Anethol
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(E)-Anethol

Item No. 29862

Technical Information
Formal Name
1-methoxy-4-(1E)-1-propen-1-yl-benzene
CAS Number
4180-23-8
Synonyms
  • trans-Anethole
  • NSC 209529
Molecular Formula
C10H12O
Formula Weight
Purity
≥95%
A low-melting solid
DMF: 15 mg/mlDMF:PBS (pH 7.2) (1:5): 0.16 mg/ml
λmax
258 nm
SMILES
C/C=C/C1=CC=C(OC)C=C1
InChi Code
InChI=1S/C10H12O/c1-3-4-9-5-7-10(11-2)8-6-9/h3-8H,1-2H3/b4-3+
InChi Key
RUVINXPYWBROJD-ONEGZZNKSA-N
Origin
Plant/Foeniculum vulgare Mill
Shipping & Storage Information
Storage
4°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    (E)-Anethol is a phenylpropanoid that has been found in P. anisum seed oil and has antifungal and antioxidant activity.1,2,3 It is active against fermentatively growing S. cerevisiae under hypoxic, but not normoxic, conditions (MIC = 100 µg/ml), and against C. parapsilosis when used at a concentration of 15% w/w.2,3 (E)-Anethol has antioxidant activity in a Trolox equivalent antioxidant capacity (TEAC) assay but does not scavenge 2,2-diphenyl-1-picrylhydrazel (DPPH) radicals in a cell-free assay.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Embong, M.B., and Hadziyev, D. Essential oils from spices grown in Alberta: Anise oil (Pimpinella anisum). J. Plant Sci. 57(3), 681-688 (1977).

    2. Fujita, K., and Kubo, I. Potentiation of fungicidal activities of trans-anethole against Saccharomyces cerevisiae under hypoxic conditions. J. Biosci. Bioeng. 98(6), 490-492 (2004).

    3. Donati, M., Mondin, A., Chen, Z., et alRadical scavenging and antimicrobial activities of Croton zehntneri, Pterodon emarginatus and Schinopsis brasiliensis essential oils and their major constituents: Estragole, trans-anethole, β-caryophyllene and myrcene. Nat. Prod. Res. 29(10), 939-946 (2014).