A fungal metabolite
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Isomer(s)
33212Ganoderic Acid C1
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Product Categories

Product Type

Biochemicals
Natural Products
Microbial Metabolites

Research Area

Cancer

Sartorypyrone B

Item No. 29949

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2R,3S,4aR,4bR,6aS,12aS,12bR,14aR)-rel-(-)-2,3-bis(acetyloxy)-2,3,4,4a,4b,5,6,6a,12,12a,12b,13,14,14a-tetradecahydro-1,1,4a,6a,9,12b-hexamethyl-1H,11H-phenanthro[2,1-b]pyrano[3,2-e]pyran-11-one
CAS Number
1452396-11-0
Molecular Formula
C30H42O7
Formula Weight
514.7
Purity
≥95%
Formulation (Request formulation change)
A solid
SMILES
CC(OC1=C2C[C@]3([H])[C@@](CC[C@@]4([H])[C@@]3(C)CC[C@]5([H])[C@]4(C)C[C@H](OC(C)=O)[C@H](OC(C)=O)C5(C)C)(C)O1)=CC2=O
InChi Code
InChI=1S/C30H42O7/c1-16-13-20(33)19-14-24-28(6)11-9-22-27(4,5)25(36-18(3)32)21(35-17(2)31)15-29(22,7)23(28)10-12-30(24,8)37-26(19)34-16/h13,21-25H,9-12,14-15H2,1-8H3/t21-,22-,23-,24-,25-,28+,29-,30-/m0/s1
InChi Key
DFAVZYUGRTVMCA-KNUPVKMWSA-N
Origin
Fungus/Neosartorya sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $267

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    10 mg

    $1,062

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    Product Description

    Sartorypyrone B is a fungal metabolite that has been found in N. fischeri and has anticancer activity.1 It inhibits the growth of MCF-7, H460, and A375 cancer cells (GI50s = 17.8, 20.5, and 25 µM, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Eamvijarn, A., Gomes, N.M., Dethoup, T., et al. Bioactive meroditerpenes and indole alkaloids from the soil fungus Neosartorya fischeri (KUFC 6344), and the marine-derived fungi Neosartorya laciniosa (KUFC 7896) and Neosartorya tsunodae (KUFC 9213). Tetrahedron 69(40), 8583-8591 (2013).