A synthetic intermediate
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6,7-Dihydro-5H-quinolin-8-one

Item No. 30480

Technical Information
Formal Name
6,7-dihydro-8(5H)-quinolinone
CAS Number
56826-69-8
Synonyms
  • 8-Aza-1-tetralone
  • 5,6-Dihydro-7(7H)-quinolinone
Molecular Formula
C9H9NO
Formula Weight
Purity
≥98%
A crystalline solid
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
230, 282 nm
SMILES
O=C1CCCC2=CC=CN=C21
InChi Code
InChI=1S/C9H9NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h2,4,6H,1,3,5H2
InChi Key
JIAKIQWNYAZUJD-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    6,7-Dihydro-5H-quinolin-8-one is a synthetic intermediate.1,2 It has been used in the synthesis of tetrahydropyridoazepinones and thiosemicarbazones with anticancer activity.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lemke, T.L., Shek, T.W., Cates, L.A., et alSynthesis of 5,6-dihydro-8(H)-quinolinone thiosemicarbazones as potential antitumor agents. J. Med. Chem. 20(10), 1351-1354 (1977).

    2. Jössang-Yanagida, A., and Gansser, C. Tetrahydropyridoazepines and tetrahydropyridoazepinones from the corresponding dihydroquinolones. J. Heterocycl. Chem. 15(2), 249-251 (1977).