A building block and an insecticide
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Abametapir

Item No. 30684

Technical Information
Formal Name
5,5′-dimethyl-2,2′-bipyridine
CAS Number
1762-34-1
Synonyms
  • 5,5′-Dimethyl-2,2′-dipyridyl
Molecular Formula
C12H12N2
Formula Weight
Purity
≥98%
A solid
DMF: 15 mg/mlDMSO: 10 mg/mlEthanol: 15 mg/mlEthanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
λmax
244, 289 nm
SMILES
CC1=CC=C(C2=CC=C(C)C=N2)N=C1
InChi Code
InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3
InChi Key
PTRATZCAGVBFIQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Abametapir is a building block and an insectide.1,2,3 It has been used in the synthesis of lanthanide coordination complexes with antifungal activity against C. albicans and divalent vancomycin derivatives with antibacterial activity against vancomycin-resistant enterococci.1,2 Abametapir is ovicidal to DDT- and permethrin-resistant head louse eggs (LC50s = 0.108, 0.121, and 0.16% in isopropanol for 0-2-, 3-5-, and 6-8-day-old eggs, respectively).3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhou, M.-X., Ren, N., Zhang, J.-J., et alSynthesis, crystal structure, thermal, luminescent property and antibacterial activity of lanthanide ternary complexes with p-chlorobenzoic acid and 5,5′-dimethyl-2,2′-bipyridine. J. Mol. Struct. 1200, 127049 (2020).

    2. Xing, B., Yu, C.-W., Ho, P.-L., et alMultivalent antibiotics via metal complexes: Potent divalent vancomycins against vancomycin-resistant enterococci. J. Med. Chem. 46(23), 4904-4909 (2003).

    3. Bowles, V.M., Yoon, K.S., Barker, S.C., et alOvicidal efficacy of abametapir against eggs of human head and body lice (Anoplura: Pediculidae). J. Med. Entomol. 54(1), 167-172 (2017).