An internal standard for the quantification of valganciclovir
Related Products
Unlabeled Version(s)
13875Valganciclovir (hydrochloride)
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Valganciclovir-d5 (hydrochloride)

Item No. 30746

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
DL-valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl-1,1,2,3,3-d5 ester, monohydrochloride
Molecular Formula
C14H17D5N6O5 • HCl
Formula Weight
395.9
Purity
≥99% deuterated forms (d1-d5)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: solubleMethanol: solubleWater: soluble
SMILES
CC(C)C(N)C(OC([2H])([2H])C(C([2H])([2H])O)([2H])OCN1C(NC(N)=NC2=O)=C2N=C1)=O.Cl
InChi Code
InChI=1S/C14H22N6O5.ClH/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22;/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22);1H/i3D2,4D2,8D;
InChi Key
ZORWARFPXPVJLW-KZUFOJGHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    500 µg

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    Cayman Chemical
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    Product Description

    Valganciclovir-d5 is intended for use as an internal standard for the quantification of valganciclovir (Item No. 13875) by GC- or LC-MS. Valganciclovir is a valyl ester prodrug form of the antiviral nucleoside analog ganciclovir (Item No. 13853). In vivo, valganciclovir (200 mg/kg) increases survival and reduces weight loss in an immunosuppressed hamster model of disseminated adenovirus type 5 (Ad5) infection.1 Formulations containing valganciclovir have been used in the prevention of post-transplant cytomegalovirus (CMV) infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Toth, K., Ying, B., Tollefson, A.E., et al. Valganciclovir inhibits human adenovirus replication and pathology in permissive immunosuppressed female and male Syrian hamsters. Viruses 7(3), 1409-1428 (2015).