An active metabolite of L-arginine and a non-proteinogenic amino acid
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L-Ornithine (hydrochloride)

Item No. 30779

Technical Information
Formal Name
L-ornithine, monohydrochloride
CAS Number
3184-13-2
Molecular Formula
C5H12N2O2 • HCl
Formula Weight
Purity
≥95%
A solid
PBS (pH 7.2): 10mg/mL
SMILES
NCCC[C@H](N)C(O)=O.Cl
InChi Code
InChI=1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1
InChi Key
GGTYBZJRPHEQDG-WCCKRBBISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    L-Ornithine is an active metabolite of L-arginine (Item No. 23703) and a non-proteinogenic amino acid.1 L-Ornithine is formed from arginine by arginase I during the final step of the urea cycle and acts as an alternate precursor to L-glutamate in the biosynthesis of proline. Exogenous administration of L-ornithine (111 mg/kg) delays the onset of ethanol-induced ataxia and decreases ethanol-induced sleeping time in rats.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Häberle, J., Boddaert, N., Burlina, A., et alSuggested guidelines for the diagnosis and management of urea cycle disorders. Orphanet J. Rare Dis. 7, 32 (2012).

    2. Breglia, R.J., Ward, C.O., and Jarowski, C.I. Effect of selected amino acids on ethanol toxicity in rats. J. Pharm. Sci. 62(1), 49-55 (1973).