A thiol-containing amino acid
Related Products
Isomer(s)
30285DL-Homocysteine
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L-Homocysteine

Item No. 30852

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
6027-13-0
Synonyms
  • NSC 43117
  • (S)-Homocysteine
Molecular Formula
C4H9NO2S
Formula Weight
135.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 5 mg/ml
SMILES
SCC[C@H](N)C(O)=O
InChi Code
InChI=1S/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)/t3-/m0/s1
InChi Key
FFFHZYDWPBMWHY-VKHMYHEASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $42

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    10 mg

    $71

    Add

    25 mg

    $132

    Add

    50 mg

    $203

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    Product Description

    L-Homocysteine is a thiol-containing amino acid and an isomer of DL-homocysteine (Item No. 30285).1 It is formed via demethylation of methionine and acts as a precursor in the biosynthesis of methionine and cysteine.1,2 Hyperhomocysteinemia (HHcy), a disorder characterized by elevated homocysteine levels due to excessive synthesis or decreased degradation of L-homocysteine, is associated with an increased risk of cardiovascular disease and stroke.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Chrysant, S.G., and Chrysant, G.S. The current status of homocysteine as a risk factor for cardiovascular disease: a mini review. Expert Rev. Cardiovasc. Ther. 16(8), 559-565 (2018).

    2. Moretti, R., and Caruso, P. The controversial role of homocysteine in neurology: From labs to clinical practice. Int. J. Mol. Sci. 20(1), 231 (2019).

    3. Perla-kaján, J., and Jakubowski, H. Dysregulation of epigenetic mechanisms of gene expression in the pathologies of hyperhomocysteinemia. Int. J. Mol. Sci. 20(13), 3140 (2019).