A vitamin K analog
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Product Categories

Product Type

Biochemicals

Research Area

Neuroscience
Seizure Disorders

2-(Isopentylamino)naphthalene-1,4-dione

Item No. 31107

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[(3-methylbutyl)amino]-1,4-naphthalenedione
CAS Number
1607447-79-9
Molecular Formula
C15H17NO2
Formula Weight
243.3
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:2): 0.33 mg/mlEthanol: 20 mg/ml
λmax
232, 271 nm
SMILES
O=C1C(NCCC(C)C)=CC(C2=CC=CC=C21)=O
InChi Code
InChI=1S/C15H17NO2/c1-10(2)7-8-16-13-9-14(17)11-5-3-4-6-12(11)15(13)18/h3-6,9-10,16H,7-8H2,1-2H3
InChi Key
JLOBMWCZCWALTQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $49

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    5 mg

    $178

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    10 mg

    $306

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    25 mg

    $645

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    Product Description

    2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.1 It inhibits spasms induced by pentylenetetrazole (PTZ; Item No. 18682) and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED50s = 349.2 and 108.1 mg/kg, respectively). It also protects mice against seizures in the 6 Hz psychomotor seizure test (ED50s = 152.7 and 263.7 mg/kg at stimulus intensities of 32 and 44 mA, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Li, X., Himes, R.A., Prosser, L.C., et al. Discovery of the first vitamin K analogue as a potential treatment of pharmacoresistant seizures. J. Med. Chem. 63(11), 5865-5878 (2020).