A mycotoxin
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Product Categories

Product Type

Biochemicals
Environmental Toxicology
Toxins
Mycotoxins

Research Area

Cancer

Fumitremorgin B

Item No. 31173

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5aR,6S,12S,14aS)-1,2,3,5a,6,11,12,14a-octahydro-5a,6-dihydroxy-9-methoxy-11-(3-methyl-2-buten-1-yl)-12-(2-methyl-1-propen-1-yl)-5H,14H-pyrrolo[1",2":4′,5′]pyrazino[1′,2′:1,6]pyrido[3,4-b]indole-5,14-dione
CAS Number
12626-17-4
Synonyms
  • Lanosulin
Molecular Formula
C27H33N3O5
Formula Weight
479.6
Purity
≥95%
Formulation (Request formulation change)
A solid
SMILES
COC1=CC=C(C(N2C/C=C(C)\C)=C1)C3=C2[C@H](/C=C(C)\C)N(C([C@@]4([H])N5CCC4)=O)[C@]([C@H]3O)(O)C5=O
InChi Code
InChI=1S/C27H33N3O5/c1-15(2)10-12-28-20-14-17(35-5)8-9-18(20)22-23(28)21(13-16(3)4)30-25(32)19-7-6-11-29(19)26(33)27(30,34)24(22)31/h8-10,13-14,19,21,24,31,34H,6-7,11-12H2,1-5H3/t19-,21-,24-,27+/m0/s1
InChi Key
WEIYXEFMCIRZHC-MWGWWEMPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $219

    Add

    5 mg

    $876

    Add
    Cayman Chemical
    Visit Our Environmental Toxicology Resource Center

    Explore additional resources to study natural toxins, pollutants including PFAS and 6-PPD-Q, and their biological effects.

    ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICES
    Product Description

    Fumitremorgin B is a mycotoxin originally isolated from A. fumigatus.1,2 It induces tremors in and is lethal to mice (LD50 = 5.4 mg/kg, i.v.). It is also toxic to brine shrimp (LC50 = 13.6 μg/ml).3 Fumitremorgin B inhibits the proliferation of U937 and PC3 cells (IC50s = 14.12 and 43.36 μM, respectively).4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yamazaki, M., Suzuki, S., and Miyaki, K. Tremorgenic toxins from Aspergillus fumigatus Fres. Chem. Pharm. Bull. (Tokyo) 19(8), 1739-1740 (1971).

    2. Yamazaki, M., and Suzuki, S. Toxicology of tremorgenic mycotoxins, fumitremorgin A and B. Dev. Toxicol. Environ. Sci. 12, 273-282 (1986).

    3. Li, X.-J., Zhang, Q., Zhang, A.-L., et al. Metabolites from Aspergillus fumigatus, an endophytic fungus associated with Melia azedarach, and their antifungal, antifeedant, and toxic activities. J. Agric. Food Chem. 60(13), 3424-3431 (2012).

    4. Wang, Y., Li, Z.-L., Bai, J., et al. 2,5-diketopiperazines from the marine-derived fungus Aspergillus fumigatus YK-7. Chem. Biodivers. 9(2), 85-93 (2012).