A tetrapeptide
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Bilaid A1

Item No. 31243

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-phenylalanyl-D-valyl-L-valyl-D-phenylalaninamide
CAS Number
2393866-02-7
Synonyms
  • H-FVVF-NH2
  • H-L-Phe-D-Val-L-Val-D-Phe-NH2
Molecular Formula
C28H39N5O4
Formula Weight
509.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: Slightly Soluble: 0.1-1 mg/mlDMSO: Sparingly Soluble: 1-10mg/mlMethanol: Sparingly Soluble: 1-10mg/ml
SMILES
O=C(N[C@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@H](CC1=CC=CC=C1)C(N)=O)=O)=O)[C@@H](N)CC2=CC=CC=C2
InChi Code
InChI=1S/C28H39N5O4/c1-17(2)23(27(36)31-22(25(30)34)16-20-13-9-6-10-14-20)33-28(37)24(18(3)4)32-26(35)21(29)15-19-11-7-5-8-12-19/h5-14,17-18,21-24H,15-16,29H2,1-4H3,(H2,30,34)(H,31,36)(H,32,35)(H,33,37)/t21-,22+,23-,24+/m0/s1
InChi Key
HOANKSJQDQJAGG-UARRHKHWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $262

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    5 mg

    $976

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    Product Description

    Bilaid A1 is a tetrapeptide agonist of the µ-opioid receptor (Ki = 750 nM in HEK293 cell membranes expressing the human receptor) and a derivative of bilaid A (Item No. 31242).1 It inhibits forskolin-induced cAMP accumulation by 47% in HEK293 cells expressing the human µ-opioid receptor when used at a concentration of 10 µM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Dekan, Z., Sianati, S., Yousuf, A., et al. A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor. Proc. Natl. Acad. Sci. USA 116(44), 22353-22358 (2019).