An internal standard for the quantification of L-tyrosine
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Unlabeled Version(s)
36333L-Tyrosine (sodium salt hydrate)
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L-Tyrosine-13C9,15N

Item No. 31256

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-tyrosine-carboxy,α,β,1,2,3,4,5,6-13C9-15N
CAS Number
202407-26-9
Synonyms
  • L-4-Hydroxyphenylalanine
  • p-Hydroxyphenylalanine
  • (–)-Tyrosine
  • p-Tyrosine
Molecular Formula
[13C]9H11[15N]O3
Formula Weight
191.1
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Slightly solubleMethanol: Slightly solublePBS (pH 7.2): Slightly soluble
λmax
223 nm
SMILES
O[13C]1=[13CH][13CH]=[13C]([13CH2][13C@H]([15NH2])[13C](O)=O)[13CH]=[13CH]1
InChi Code
InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1/i1+1,2+1,3+1,4+1,5+1,6+1,7+1,8+1,9+1,10+1
InChi Key
OUYCCCASQSFEME-CMLFETTRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 mg

    $175

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    50 mg

    $333

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    100 mg

    $630

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    Product Description

    L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a conditionally essential amino acid.1 It is produced by hydroxylation of phenylalanine by phenylalanine hydroxylase but can also be obtained from dietary sources or degradation of endogenous proteins, resulting in L-tyrosine release.1,2 L-Tyrosine is a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones.3 Plasma, skeletal muscle, and erythrocyte levels of L-tyrosine are decreased in patients with chronic kidney disease.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kopple, J.D. Phenylalanine and tyrosine metabolism in chronic kidney failure. J. Nutr. 137(6 Suppl 1), 1586S-1590S (2007).

    2. Webster, D., and Wildgoose, J. Tyrosine supplementation for phenylketonuria. Cochrane DB Syst. Rev. 6, CD001507 (2013).

    3. Slominski, A., and Paus, R. Towards defining receptors for L-tyrosine and L-DOPA. Mol. Cell Endocrinol. 99(2), C7-C11 (1994).