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ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICESZearalenone-13C18 is intended for use as an internal standard for the quantification of zearalenone (Item No. 11353) by GC- or LC-MS. Zearalenone is a mycotoxin that has been found in Fusarium and has estrogenic activities.1 It binds to human estrogen receptor α (ERα) and ERβ (IC50s = 9 and 5.8 nM, respectively).2 Zearalenone induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male pigs.3 Zearalenone (1.5-5 mg/kg of diet) induces hyperestrogenism in pigs. It also induces degeneration of meiotic chromatin in oocytes and reduces fertility in pigs when administered at a dose of 200 µg/kg.4 Zearalenone has been found as a contaminant in wheat, maize, and barley and livestock feeds.3,4
WARNING This product is not for human or veterinary use.
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