An antimicrobial agent
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Isomer(s)
32582SSAA09E1
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2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide

Item No. 31385

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[1-(2-thienyl)ethylidene]-hydrazinecarbothioamide
CAS Number
5351-71-3
Synonyms
  • NSC 707
  • 1-(Thiophen-2-yl)ethanone thiosemicarbazone
Molecular Formula
C7H9N3S2
Formula Weight
199.3
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:4): 0.20 mg/mlEthanol: 1 mg/ml
λmax
248, 327 nm
SMILES
S=C(N/N=C(C)/C1=CC=CS1)N
InChi Code
InChI=1S/C7H9N3S2/c1-5(9-10-7(8)11)6-3-2-4-12-6/h2-4H,1H3,(H3,8,10,11)/b9-5+
InChi Key
PJVHAJJEMJNPHN-WEVVVXLNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $49

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    10 mg

    $93

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    25 mg

    $213

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    50 mg

    $400

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    Cayman Chemical
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    Product Description

    2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is an antimicrobial agent.1 It is active against the Gram-negative bacteria E. coli, P. aeruginosa, and S. marcescens (MICs = 64, 100, and 70 μg/ml, respectively), the Gram-positive bacteria S. aureus, M. luteus, and B. cereus (MICs = 130, 100, and 50 μg/ml, respectively), and the fungi C. albicans, G. candidum, T. rubrum, F. oxysporum, A. flavus, and S. brevicaulis (MICs = 69-120 μg/ml). 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is also a precursor in the synthesis of other antimicrobial agents, as well as compounds with anticancer activity.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Youssef, M.S.K., and Abeed, A.A.O. Synthesis and antimicrobial activity of some novel 2-thienyl substituted heterocycles. Heterocycl. Commun. 20(1), 25-31 (2014).

    2. Gomha, S.M., Edrees, M.M., and Altalbawy, F.M.A. Synthesis and characterization of some new bis-pyrazolyl-thiazoles incorporating the thiophene moiety as potent anti-tumor agents. Int. J. Mol. Sci. 17(9), 1499 (2016).