A ginsenoside with immunomodulatory activity
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Ginsenoside F3

Item No. 31409

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,6α,12β)-3,6,12-trihydroxydammar-24-en-20-yl 6-O-α-L-arabinopyranosyl-β-D-glucopyranoside
CAS Number
62025-50-7
Molecular Formula
C41H70O13
Formula Weight
771.0
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: solubleEthanol: solubleMethanol: soluble
SMILES
O[C@H]1[C@@]2([H])[C@](CC[C@]2([H])[C@@](CC/C=C(C)/C)(C)O[C@@H]3O[C@H](CO[C@@H]4OC[C@H](O)[C@H](O)[C@H]4O)[C@@H](O)[C@H](O)[C@H]3O)(C)[C@]5(C)C[C@H](O)[C@]6([H])[C@@](CC[C@H](O)C6(C)C)(C)[C@@]5([H])C1
InChi Code
InChI=1S/C41H70O13/c1-20(2)10-9-13-41(8,54-36-33(50)31(48)30(47)25(53-36)19-52-35-32(49)29(46)24(44)18-51-35)21-11-15-39(6)28(21)22(42)16-26-38(5)14-12-27(45)37(3,4)34(38)23(43)17-40(26,39)7/h10,21-36,42-50H,9,11-19H2,1-8H3/t21-,22+,23-,24-,25+,26+,27-,28-,29-,30+,31-,32+,33+,34-,35-,36-,38+,39+,40+,41-/m0/s1
InChi Key
HJRVLGWTJSLQIG-ABNMXWHVSA-N
Origin
Plant/Ginseng root
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $103

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    5 mg

    $454

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    10 mg

    $753

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    Product Description

    Ginsenoside F3 is a ginsenoside that has been found in P. ginseng and has immunomodulatory activity.1 It increases proliferation of isolated mouse spleen cells and the production of IL-2 and IFN-γ, as well as decreases the production of IL-4 and IL-10, when used at concentrations ranging from 0.1 to 100 µM. Ginsenoside F3 (10 µM) also increases the DNA binding activity of NF-κB induced by concanavalin A (Item No. 14951) in isolated mouse spleen cells.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yu, J., Dou, D., Chen, X., et al. Immunoenhancing activity of protopanaxatriol-type ginsenoside-F3 in murine spleen cells. Acta Pharmacol. Sin. 25(12), 1671-1676 (2004).