A DGK inhibitor
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Dioctanoyl Glycol

Item No. 31515

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
octanoic acid, 1,1′-(1,2-ethanediyl) ester
CAS Number
627-86-1
Synonyms
  • Dioctanoyl Glycol
  • diC8-Ethylene Glycol
  • Ethylene Glycol Dioctanoate
  • 8:0 Ethylene Glycol
  • NSC 97300
  • SFE 18:1;O2
Molecular Formula
C18H34O4
Formula Weight
314.5
Purity
≥98%
Formulation (Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/ml
SMILES
O=C(CCCCCCC)OCCOC(CCCCCCC)=O
InChi Code
InChI=1S/C18H34O4/c1-3-5-7-9-11-13-17(19)21-15-16-22-18(20)14-12-10-8-6-4-2/h3-16H2,1-2H3
InChi Key
HTNFLUQQANUSLR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $33

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    10 mg

    $60

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    25 mg

    $108

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    50 mg

    $149

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    Product Description

    Dioctanoyl glycol is a diacylglycerol kinase (DGK) inhibitor (Ki = 58 μM).1 It reduces basal and thrombin-stimulated phosphatidic acid levels in washed isolated human platelets when used at concentrations of 30, 100, and 500 μM.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bishop, W.R., Ganong, B.R., and Bell, R.M. Attenuation of sn-1,2-diacyglycerol second messengers by diacylglycerol kinase. Inhibition by diacyglycerol analogs in vitro and in human platelets. The Journal of Biological Chemisty 261(15), 6993-7000 (1986).