A methylated purine nucleoside
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N1-Methylguanosine

Item No. 31737

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-methyl-guanosine
CAS Number
2140-65-0
Synonyms
  • 1-Methylguanosine
  • m1G
  • NSC 70897
Molecular Formula
C11H15N5O5
Formula Weight
297.3
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 1 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
257 nm
SMILES
O=C1C2=C(N=C(N)N1C)N([C@]3([H])O[C@H](CO)[C@@H](O)[C@H]3O)C=N2
InChi Code
InChI=1S/C11H15N5O5/c1-15-9(20)5-8(14-11(15)12)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14)/t4-,6-,7-,10-/m1/s1
InChi Key
UTAIYTHAJQNQDW-KQYNXXCUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $36

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    5 mg

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    10 mg

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    25 mg

    $378

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    Cayman Chemical
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    Product Description

    N1-Methylguanosine (m1G) is a methylated purine nucleoside formed during the degradation of tRNA and a biological end product.1,2 Levels of m1G are increased in the urine of patients with malignant tumors compared to those with benign or no tumors and have been used as biomarkers of cancer.3,1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liebich, H.M., Müller-Hagedorn, S., Klaus, F., et al. Chromatographic, capillary electrophoretic and matrix-assisted laser desorption ionization time-of-flight mass spectrometry analysis of urinary modified nucleosides as tumor markers. J. Chromatogr. A. 1071(1-2), 271-275 (2005).

    2. Mitchell, E.P., Evans, L., Schultz, P., et al. Modified nucleosides in human serum. J. Chromatogr. 581(1), 31-40 (1992).

    3. Seidel, A., Brunner, S., Seidel, P., et al. Modified nucleosides: An accurate tumour marker for clinical diagnosis of cancer, early detection and therapy control. Br. J. Cancer. 94(11), 1726-1733 (2006).