A diterpene alkaloid with diverse biological activities
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Delsoline

Item No. 31748

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(1α,6β,14α,16β)-20-ethyl-6,14,16-trimethoxy-4-(methoxymethyl)-aconitane-1,7,8-triol
CAS Number
509-18-2
Synonyms
  • Acomonine
Molecular Formula
C25H41NO7
Formula Weight
467.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: solubleMethanol: soluble
SMILES
O[C@@H](CC1)C(C(N2CC)C3(O)[C@H]4OC)([C@@](C[C@H]5[C@]6([H])OC)([H])[C@H]6[C@@]3(C[C@@H]5OC)O)[C@@]4([H])[C@@]1(C2)COC
InChi Code
InChI=1S/C25H41NO7/c1-6-26-11-22(12-30-2)8-7-16(27)24-14-9-13-15(31-3)10-23(28,17(14)18(13)32-4)25(29,21(24)26)20(33-5)19(22)24/h13-21,27-29H,6-12H2,1-5H3/t13-,14-,15+,16+,17-,18+,19-,20+,21?,22+,23-,24?,25?/m1/s1
InChi Key
JVBLTQQBEQQLEV-WZROKYDKSA-N
Origin
Plant/Aconitum carmichaelii
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $50

    Add

    5 mg

    $110

    Add

    10 mg

    $147

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    Delsoline is a diterpene alkaloid that has been found in Delphinium and has diverse biological activities.1,2,3 It inhibits binding of α-bungarotoxin (Item No. 16385) to rat neuronal α7 nicotinic acetylcholine receptors (nAChRs; IC50 = 19 µM).1 Delsoline (3 mg/ml) is repellent against adult red flour beetles (T. castaneum) in a filter paper assay.2 In vivo, delsoline (75 mg/kg) lowers systolic blood pressure in a rat model of left renal artery ligation-induced hypertension.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hardick, D.J., Blagbrough, I.S., Cooper, G., et al. Nudicauline and elatine as potent norditerpenoid ligands at rat neuronal alpha-bungarotoxin binding sites: Importance of the 2-(methylsuccinimido)benzoyl moiety for neuronal nicotinic acetylcholine receptor binding. J. Med. Chem. 39(24), 4860-4866 (1996).

    2. Ulubelen, A., Meriçli, A.H., Kilinçer, N., et al. Insect repellent activity of diterpenoid alkaloids. Phytother. Res. 15(2), 170-171 (2001).

    3. Lian, Q.S., and Feng, G.H. Hypotensive effect of delsoline. Zhongguo Yaoli Xuebao 6(1), 37-40 (1985).