A glycopeptide antibiotic
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Parvodicin C2

Item No. 32542

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-56-O-[2-deoxy-2-[(1-oxododecyl)amino]-β-D-glucopyranuronosyl]-42-O-α-D-mannopyranosyl-N15-methyl-ristomycin A aglycone
CAS Number
110882-85-4
Synonyms
  • Antibiotic A40926 B1
Molecular Formula
C83H88Cl2N8O29
Formula Weight
1732.5
Purity
≥90%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 10 mg/mlDMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml
SMILES
OC([C@H](C1=CC(O)=CC(O[C@@H](O[C@H](CO)[C@H]2O)[C@@H](O)[C@H]2O)=C1C3=CC([C@]4(NC([C@@]([H])5NC([C@]([H])(C6=C(Cl)C(O)=CC7=C6)NC([C@@](CC(C=C8)=CC=C8O9)(NC([C@H](NC)C%10=CC(O7)=C(O)C=C%10)=O)[H])=O)=O)=O)[H])=CC=C3O)NC([C@]([H])([C@H](O)C%11=CC=C(C(Cl)=C%11)OC%12=C(O[C@@H]([C@H](NC(CCCCCCCCCCC)=O)[C@@H](O)[C@@H]%13O)O[C@@H]%13C(O)=O)C9=CC5=C%12)NC4=O)=O)=O
InChi Code
InChI=1S/C83H88Cl2N8O29/c1-3-4-5-6-7-8-9-10-11-12-56(99)88-65-68(102)70(104)73(81(114)115)122-82(65)121-72-53-27-38-28-54(72)118-50-22-17-37(25-45(50)84)66(100)64-79(111)92-63(80(112)113)43-29-39(95)30-52(119-83-71(105)69(103)67(101)55(33-94)120-83)57(43)42-24-35(15-20-47(42)96)60(76(108)93-64)89-77(109)61(38)90-78(110)62-44-31-41(32-49(98)58(44)85)117-51-26-36(16-21-48(51)97)59(86-2)75(107)87-46(74(106)91-62)23-34-13-18-40(116-53)19-14-34/h13-22,24-32,46,55,59-71,73,82-83,86,94-98,100-105H,3-12,23,33H2,1-2H3,(H,87,107)(H,88,99)(H,89,109)(H,90,110)(H,91,106)(H,92,111)(H,93,108)(H,112,113)(H,114,115)/t46-,55-,59-,60-,61-,62+,63+,64+,65-,66-,67-,68-,69+,70+,71+,73+,82-,83+/m1/s1
InChi Key
IMGYVEMZPBHISV-PSDJNXLUSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    Parvodicin C2 is a glycopeptide antibiotic originally isolated from A. parvosata and a component of parvodicin complex (Item No. 24036).1 It is also a component of the A40926 antibiotic complex, which has been used as a precursor in the synthesis of the antibiotic dalbavancin (Item No. 21161).2 Parvodicin C2 is active against methicillin-sensitive strains of S. aureus, S. epidermidis, and S. saprophyticus (MICs = 0.4-12.5 μg/ml), as well as methicillin-resistant strains of S. aureus, S. hemolyticus, and E. faecalis (MICs = 0.2-50 μg/ml).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Christensen, S.B., Allaudeen, H.S., Burke, M.R., et al. Parvodicin, a novel glycopeptide from a new species, Actinomadura parvosata: Discovery, taxonomy, activity and structure elucidation. J. Antibiot. (Tokyo) 40(7), 970-990 (1987).

    2. Jovetic, S., Feroggio, M., Marinelli, F., et al. Factors influencing cell fatty acid composition and A40926 antibiotic complex production in Nonomuraea sp. ATCC 39727. J. Ind. Microbiol. Biotechnol. 35(10), 1131-1138 (2008).