A microbial metabolite with antifungal, fungicidal, and antiviral activities
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Benanomicin A

Item No. 32886

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[[(5S,6S)-5-[(6-deoxy-3-O-β-D-xylopyranosyl-β-D-galactopyranosyl)oxy]-5,6,8,13-tetrahydro-1,6,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxobenzo[a]naphthacen-2-yl]carbonyl]-D-alanine
CAS Number
116249-65-1
Molecular Formula
C39H41NO19
Formula Weight
827.7
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Ethanol: soluble
λmax
294 nm
SMILES
OC1=C2C3=C(O)C(C(C4=CC(OC)=CC(O)=C4C5=O)=O)=C5C=C3[C@@H]([C@H](C2=CC(C)=C1C(N[C@H](C)C(O)=O)=O)O[C@H]6[C@@H]([C@H]([C@H]([C@H](O6)C)O)O[C@H]7[C@@H]([C@H]([C@@H](CO7)O)O)O)O)O
InChi Code
InChI=1S/C39H41NO19/c1-10-5-17-23(30(48)20(10)36(52)40-11(2)37(53)54)22-15(8-16-24(31(22)49)27(45)14-6-13(55-4)7-18(41)21(14)26(16)44)28(46)34(17)58-39-33(51)35(25(43)12(3)57-39)59-38-32(50)29(47)19(42)9-56-38/h5-8,11-12,19,25,28-29,32-35,38-39,41-43,46-51H,9H2,1-4H3,(H,40,52)(H,53,54)/t11-,12-,19-,25+,28+,29+,32-,33-,34+,35+,38+,39+/m1/s1
InChi Key
GOYUMGXIFMGKFN-NUVDETJMSA-N
Origin
Bacterium/Actinomadura sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $623

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    Product Description

    Benanomicin A is a microbial metabolite that has been found in Actinomycetes and has antifungal, fungicidal, and antiviral activities.1,2 It is active against a variety of mammalian and plant pathogenic fungi, including C. albicans, T. mentagrophytes, C. neoformans, P. oryzae, and A. niger (MICs = 3.13-50 µg/ml).1 Benanomicin A inhibits HIV-1 viral infection in MT-4 cells in a concentration-dependent manner.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Takeuchi, T., Hara, T., Naganawa, H., et al. New antifungal antibiotics, benanomicins A and B from an actinomycete. J. Antibiot. (Tokyo) 41(6), 807-811 (1987).

    2. Kondo, S., Gomi, S., Ikeda, D., et al. Antifungal and antiviral activities of benanomicins and their analogues. J. Antibiot. (Tokyo) 44(11), 1228-1236 (1990).