A triazole fungicide
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Cyproconazole

Item No. 32947

Technical Information
Formal Name
α-(4-chlorophenyl)-α-(1-cyclopropylethyl)-1H-1,2,4-triazole-1-ethanol
CAS Number
94361-06-5
Synonyms
  • SAN 619F
Molecular Formula
C15H18ClN3O
Formula Weight
Purity
≥98% (mixture of isomers)
Formulation
A crystalline solid
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:5): 0.16 mg/mlEthanol: 1 mg/ml
λmax
221 nm
SMILES
ClC1=CC=C(C(CN2N=CN=C2)(C(C3CC3)C)O)C=C1
InChi Code
InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3
InChi Key
UFNOUKDBUJZYDE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Cyproconazole is a triazole fungicide.1 It reduces mycelial growth of A. mellea on grapevine roots. Cyproconazole also reduces defoliation of rose plants induced by the plant pathogenic fungus D. rosae.2 It is lethal to the freshwater invertebrates C. riparius and D. tigrina (LC50s = 17.46 and 47.38 mg/L, respectively, in tank water).3 Cyproconazole induces liver hypertrophy and fat vacuolation, as well as induces hepatocellular adenoma and carcinoma formation, in mice.4 Formulations containing cyproconazole have been used as fungicides in agricultural settings.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aguín, O., Mansilla, J.P., and Sainz, M.J. In vitro selection of an effective fungicide against Armillaria mellea and control of white root rot of grapevine in the field. Pest. Manag. Sci. 62(3), 223-228 (2006).

    2. Bowen, K.L., and Roark, R.S. Management of black spot of rose with winter fungicide treatment. Plant Dis. 85(4), 393-398 (2001).

    3. Saraiva, A.S., Sarmento, R.A., Golovko, O., et al. Lethal and sub-lethal effects of cyproconazole on freshwater organisms: A case study with Chironomus riparius and Dugesia tigrina. Environ. Sci. Pollut. Res. Int. 25(12), 12169-12176 (2018).

    4. Peffer, R.C., Moggs, J.G., Pastoor, T., et al. Mouse liver effects of cyproconazole, a triazole fungicide: Role of the constitutive androstane receptor. Toxicol. Sci. 99(1), 315-325 (2007).