A triterpene with antiviral and hepatoprotective activities
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Betulin 3,28-diacetate

Item No. 33028

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3β,28-diacetate lup-20(29)-ene-3,28-diol
CAS Number
1721-69-3
Synonyms
  • Betulin Diacetate
  • NSC 38876
Molecular Formula
C34H54O4
Formula Weight
526.8
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Chloroform: 10 mg/mlDMF: slightly solubleDMSO: slightly soluble
SMILES
C[C@]1([C@]2([C@]([C@@]3([C@@](C(C)([C@H](CC3)OC(C)=O)C)([H])CC2)C)([H])CC4)C)[C@@]4([H])[C@]([C@@H](CC5)C(C)=C)([H])[C@@]5(COC(C)=O)CC1
InChi Code
InChI=1S/C34H54O4/c1-21(2)24-12-17-34(20-37-22(3)35)19-18-32(8)25(29(24)34)10-11-27-31(7)15-14-28(38-23(4)36)30(5,6)26(31)13-16-33(27,32)9/h24-29H,1,10-20H2,2-9H3/t24-,25+,26-,27+,28-,29+,31-,32+,33+,34+/m0/s1
InChi Key
MIROITGPMGDCGI-MQXQNARFSA-N
Origin
Plant/Betula pendula
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $36

    Add

    5 mg

    $128

    Add

    10 mg

    $203

    Add

    25 mg

    $420

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    Betulin 3,28-diacetate is a triterpene and derivative of betulin (Item No. 11041) that has been found in B. pendula and has antiviral and hepatoprotective activities.1,2,3 It inhibits Semliki Forest virus (SFV) replication in virus-infected Huh7 cells (IC50 = 9.1 µM).2 Betulin 3,28-diacetate (20 mg/kg) increases the rate of bile secretion, a marker of hepatic function, in rat models of hepatitis induced by carbon tetrachloride, ethanol, or tetracycline (Item No. 14328).3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Salah, A., and Bakibaev, A. Effective method of extraction of betulin diacetate from birch bark. J. Nat. Prod. Resour. 3(1), 90-93 (2017).

    2. Pohjala, L., Alakurtti, S., Ahola, T., et al. Betulin-derived compounds as inhibitors of alphavirus replication. J. Nat. Prod. 72(11), 1917-1926 (2009).

    3. Flekhter, O.B., Karachurina, L.T., Poroikov, V.V., et al. The synthesis and hepatoprotective activity of esters of the lupane group triterpenoids. Russ. J. Bioorg. Chem. 26(3), 192-200 (2000).