A polyketide with fungicidal and plant growth inhibitory properties
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7-dechloro Griseofulvin

Item No. 33116

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(1′S,6′R)-2′,4,6-trimethoxy-6′-methyl-spiro[benzofuran-2(3H), 1′-[2]cyclohexene]-3,4′-dione
CAS Number
3680-32-8
Molecular Formula
C17H18O6
Formula Weight
318.3
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Acetone: very slightly solubleDMSO: slightly solubleEthyl Acetate: very slightly, heated
SMILES
O=C1[C@@]2([C@H](C)CC(C=C2OC)=O)OC3=CC(OC)=CC(OC)=C31
InChi Code
InChI=1S/C17H18O6/c1-9-5-10(18)6-14(22-4)17(9)16(19)15-12(21-3)7-11(20-2)8-13(15)23-17/h6-9H,5H2,1-4H3/t9-,17+/m1/s1
InChi Key
QPCYNIYZPDJCMB-XLFHBGCDSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $169

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    Product Description

    7-dechloro Griseofulvin is a polyketide and derivative of griseofulvin (Item No. 19461) that has been found in Penicillium and has fungicidal and plant growth inhibitory properties.1,2,3 It is active against the plant pathogenic fungi B. cinerea, C. orbiculare, R. solani, and S. sclerotiorum with EC50 values of 40, 81.7, 43.9, and 28.5 µg/ml, respectively.2 7-dechloro Griseofulvin (1-300 mg/L) inhibits hypocotyl and root growth of lettuce seedlings.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhang, H.-M., Ju, C.-X., Li, G., et al. Dimeric 1,4-benzoquinone derivatives with cytotoxic activities from the marine-derived fungus Penicillium sp. L129. Mar. Drugs 17(7), 383 (2019).

    2. Zhao, J.H., Zhang, Y.L., Wang, L.W., et al. Bioactive secondary metabolites from Nigrospora sp. LLGLM003, an endophytic fungus of the medicinal plant Moringa oleifera Lam. World J. Microbiol. Biotechnol. 28(5), 2107-2112 (2012).

    3. Kimura, Y., Shiojima, K., Nakajima, H., et al. Structure and biological activity of plant growth regulators produced by Penicillium sp. No. 31f. Biosci. Biotechnol. Biochem. 56(7), 1138-1139 (1992).