A PI3K p110α inhibitor
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MDK34597

Item No. 33137

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-[4-(4-morpholinyl)pyrido[3′,2′:4,5]furo[3,2-d]pyrimidin-2-yl]-benzenamine
CAS Number
371934-59-7
Molecular Formula
C19H17N5O2
Formula Weight
347.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
λmax
232, 285 nm
SMILES
NC1=CC=CC(C(N=C2N3CCOCC3)=NC4=C2OC5=NC=CC=C54)=C1
InChi Code
InChI=1S/C19H17N5O2/c20-13-4-1-3-12(11-13)17-22-15-14-5-2-6-21-19(14)26-16(15)18(23-17)24-7-9-25-10-8-24/h1-6,11H,7-10,20H2
InChi Key
RQPKSOWRJPRYCN-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $81

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    5 mg

    $357

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    10 mg

    $633

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    Product Description

    MDK34697 is an inhibitor of PI3K p110α (IC50 = 141.25 nM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Li, Y., Wang, Y., and Zhang, F. Pharmacophore modeling and 3D-QSAR analysis of phosphoinositide 3-kinase p110α inhibitors. J. Mol. Model 16(9), 1449-1460 (2010).