A synthetic progestin
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Isomer(s)
20941Norethindrone
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Norethynodrel

Item No. 33230

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
17α-hydroxy-19-norpregn-5(10)-en-20-yn-3-one
CAS Number
68-23-5
Synonyms
  • Norethinodrel
  • NSC 15432
  • SC-4642
Molecular Formula
C20H26O2
Formula Weight
298.4
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: Slightly solubleMethanol: Slightly soluble
SMILES
C[C@@]12[C@](CC[C@@]2(O)C#C)([H])[C@@]3([H])[C@](C4=C(CC(CC4)=O)CC3)([H])CC1
InChi Code
InChI=1S/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,16-18,22H,4-12H2,2H3/t16-,17-,18+,19+,20+/m1/s1
InChi Key
ICTXHFFSOAJUMG-SLHNCBLASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

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    Product Description

    Norethynodrel is a synthetic progestin.1,2 In vivo, norethynodrel (10 mg/animal per day) reduces fetal implantation and induces fetal resorption in mated female rats.2 Formulations containing norethynodrel have been used as oral contraceptives.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kubli-Garfias, C., González-Mariscal, G., Vásquez-Ramírez, R., et al. Bimodal binding and free energy of the progesterone receptor in the induction of female sexual receptivity by progesterone and synthetic progestins. J. Steroid Biochem. Mol. Biol. 133, 43-50 (2013).

    2. Davis, B.K. Termination of pregnancy in the rat with norethynodrel. Nature 197, 308-309 (1963).