An internal standard for the quantification of tedizolid
Related Products
Unlabeled Version(s)
32952Tedizolid
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Tedizolid-13C-d3

Item No. 33290

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5R)-3-[3-fluoro-4-[6-[2-(methyl-13C-d3)-2H-tetrazol-5-yl]-3-pyridinyl]phenyl]-5-(hydroxymethyl)-2-oxazolidinone
CAS Number
2931763-72-1
Synonyms
  • TR-700-13C-d3
Molecular Formula
C16[13C]H12D3FN6O3
Formula Weight
374.4
Purity
≥99% deuterated forms (d1-d3)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Acetonitrile: solubleDMSO: solubleMethanol: soluble
SMILES
FC1=CC(N2C[C@H](CO)OC2=O)=CC=C1C3=CN=C(C4=NN([13C]([2H])([2H])[2H])N=N4)C=C3
InChi Code
InChI=1S/C17H15FN6O3/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(9-25)27-17(24)26/h2-7,12,25H,8-9H2,1H3/t12-/m1/s1/i1+1D3
InChi Key
XFALPSLJIHVRKE-JMQKSPSZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $401

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    Tedizolid-13C-d3 is intended for use as an internal standard for the quantification of tedizolid (Item No. 32952) by GC- or LC-MS. Tedizolid is an oxazolidinone antibiotic and active metabolite of the antibiotic tedizolid phosphate (Item No. 23729).1 Tedizolid phosphate is converted to tedizolid by phosphatases in vivo. It is active against a wide variety of clinical isolates, including isolates of methicillin-resistant S. aureus (MRSA), E. faecalis, and penicillin-susceptible S. pneumoniae (MICs = 0.5, 0.5, and 0.25 µg/ml, respectively), as well as isolates of anaerobic bacteria (MICs = 0.25-4 µg/ml). Tedizolid protects against mortality in a mouse model of systemic methicillin-susceptible S. aureus (MSSA) infection (ED50 = 8.8 mg/kg).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Schaadt, R., Sweeney, D.A., Shinabarger, D., et al. In vitro activity of TR-700, the active ingredient of the antibacterial prodrug TR-701, a novel oxazolidinone antibacterial agent. Antimicrob. Agents Chemother. 53(8), 3236-3239 (2009).

    2. Im, W.B., Choi, S.H., Park, J.-Y., et al. Discovery of torezolid as a novel 5-hydroxymethyl-oxazolidinone antibacterial agent. Eur. J. Med. Chem. 46(4), 1027-1039 (2011).