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Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.
DOWNLOAD NOWNitrofurantoin-13C3 is intended for use as an internal standard for the quantification of nitrofurantoin (Item No. 23510) by GC- or LC-MS. Nitrofurantoin is a nitrofuran antibiotic.1 In vivo, nitrofurantoin (25-100 mg/kg) reduces E. coli replication and abscess formation in the renal medulla of infected rats in a dose-dependent manner. It prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates of P. mirabilis. Nitrofurantoin also prevents alkalization of urine, as well as calculi and abscess formation, in a rat model of P. vulgaris urinary tract infection.2 Formulations containing nitrofurantoin have been used to treat urinary tract infections.
WARNING This product is not for human or veterinary use.
1. Site of action of nitrofurantoin in experimental urinary tract infection. Appl. Microbiol. 18(4), 547-549 (1969).
2. Proteus vulgaris urinary tract infections in rats; treatment with nitrofuran derivatives. Br. J. Pharmacol. Chemother. 19(2), 306-312 (1962).