A bacterial metabolite with nematocidal activity
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Isomer(s)
27022K-TMZ 22440PKF118-310
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Fervenulin

Item No. 33499

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6,8-dimethyl-pyrimido[5,4-e]-1,2,4-triazine-5,7(6H,8H)-dione
CAS Number
483-57-8
Synonyms
  • NSC 68158
  • Planomycin
  • U 7118
Molecular Formula
C7H7N5O2
Formula Weight
193.2
Purity
≥95%
Formulation
A solid
SMILES
O=C1C2=NC=NN=C2N(C)C(N1C)=O
InChi Code
InChI=1S/C7H7N5O2/c1-11-5-4(8-3-9-10-5)6(13)12(2)7(11)14/h3H,1-2H3
InChi Key
RRTKVYSLIGQWCO-UHFFFAOYSA-N
Origin
Bacterium/Streptomyces sp.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

    $222

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    25 mg

    $882

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    Cayman Chemical
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    Product Description

    Fervenulin is a bacterial metabolite originally isolated from Streptomyces that has nematocidal activity.1,2 It inhibits egg hatching of the root-knot nematode M. incognita (MIC = 30 µg/ml), as well as induces mortality in M. incognita second-stage juveniles when used at a concentration of 250 µg/ml.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. DeBoer, C., Dietz, A., Evans, J.S., et al. Fervenulin, a new crystalline antibiotic. I. Discovery and biological activities. Antibiot Annu. 7, 220-226 (1960).

    2. Ruanpanun, P., Laatsch, H., Tangchitsomkid, N., et al. Nematicidal activity of fervenulin isolated from a nematicidal actinomycete, Streptomyces sp. CMU-MH021, on Meloidogyne incognita. World J. Microbiol. Biotechnol. 27(6), 1373-1380 (2011).