An internal standard for the quantification of tryptamine
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Unlabeled Version(s)
20995Tryptamine
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Tryptamine-d4 (hydrochloride)

Item No. 33538

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1H-indole-3-ethan-α,α,β,β-d4-amine, monohydrochloride
CAS Number
340257-60-5
Synonyms
  • 3-Indoleethylamine-d4
Molecular Formula
C10H8D4N2 • HCl
Formula Weight
200.7
Purity
≥99% deuterated forms (d1-d4)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: slightly, heatedMethanol: slightly solubleWater: slightly soluble
SMILES
NC([2H])([2H])C([2H])([2H])C1=CNC2=CC=CC=C12.Cl
InChi Code
InChI=1S/C10H12N2.ClH/c11-6-5-8-7-12-10-4-2-1-3-9(8)10;/h1-4,7,12H,5-6,11H2;1H/i5D2,6D2;
InChi Key
KDFBGNBTTMPNIG-NXMSQKFDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $81

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    5 mg

    $376

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    Product Description

    Tryptamine-d4 is intended for use as an internal standard for the quantification of tryptamine (Item No. 20995) by GC- or LC-MS. Tryptamine is an indole alkaloid and intermediate in the biosynthesis of serotonin and the phytohormone melatonin in plants.1,2 It increases levels of the terpenoid indole alkaloids ajmalicine (Item No. 31213), strictosidine, and catharanthine (tartrate) (Item No. 11695) in cultures of C. roseus.3 Tryptamine is also a product of tryptophan metabolism in mammals.4 Tryptamine derivatives have been synthetically produced as hallucinogenic drugs of abuse that act on the serotonergic system.5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Arnao, M.B. Phytomelatonin: Discovery, content, and role in plants. Adv. Bot. 2014:815769, (2014).

    2. Fan, J., Xie, Y., Zhang, Z., et al. Melatonin: A multifunctional factor in plants. Int. J. Mol. Sci. 19(5), E1528 (2018).

    3. Almagro, L., Fernández-Pérez, F., and Pedreño, M.A. Indole alkaloids from Catharanthus roseus: Bioproduction and their effect on human health. Molecules 20(2), 2973-3000 (2015).

    4. Berumen, L.C., Rodríguez, A., Miledi, R., et al. Serotonin receptors in hippocampus. Sci. World J. 2012:823493, (2012).

    5. Araujo, A.M., Carvalho, F., Bastos, M.L., et al. The hallucinogenic world of tryptamines: An updated review. Arch. Toxicol. 89(8), 1151-1173 (2015).