A bacterial metabolite with antifungal and fungicidal activities
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Tubermycin B

Item No. 33659

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-phenazinecarboxylic acid
CAS Number
2538-68-3
Synonyms
  • NSC 15851
  • PCA
  • Phenazine-1-carboxylate
  • Phenazinecarboxylic Acid
  • Shenqinmycin
Molecular Formula
C13H8N2O2
Formula Weight
224.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 1 mg/mlDMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml
λmax
250 nm
SMILES
O=C(C1=C2N=C3C=CC=CC3=NC2=CC=C1)O
InChi Code
InChI=1S/C13H8N2O2/c16-13(17)8-4-3-7-11-12(8)15-10-6-2-1-5-9(10)14-11/h1-7H,(H,16,17)
InChi Key
JGCSKOVQDXEQHI-UHFFFAOYSA-N
Origin
Bacterium/Pseudomonas fluorescens
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

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    10 mg

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    25 mg

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    Cayman Chemical
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    Product Description

    Tubermycin B is a bacterial metabolite that has been found in Pseudomonas and has antifungal and fungicidal activities.1,2 It is active against A. flavus, C. albicans, and T. rubrum (MICs = 64, 8, and 4 µg/ml, respectively), as well as the plant pathogenic fungi F. oxysporum and R. solani (MICs = 125 and 32 µg/ml, respectively).1 Tubermycin B (10-500 µg/ml) prevents the development of foliar anthracnose lesions in cucumber plants infected with the plant pathogenic fungus C. orbiculare.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gorantla, J.N., Kumar, S.N., Nisha, G.V., et al. Purification and characterization of antifungal phenazines from a fluorescent Pseudomonas strain FPO4 against medically important fungi. J. Mycol. Med. 24(3), 185-192 (2014).

    2. Lee, J.Y., Moon, S.S., and Hwang, B.K. Isolation and in vitro and in vivo activity against Phytophthora capsici and Colletotrichum orbiculare of phenazine-1-carboxylic acid from Pseudomonas aeruginosa strain GC-B26. Pest. Manag. Sci. 59(8), 872-882 (2003).