A flavonoid glycoside with diverse biological activities
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Isomer(s)
35805Saponarin 33403Vicenin-2
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Luteolin 7-O-Rutinoside

Item No. 34035

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5-hydroxy-4H-1-benzopyran-4-one
CAS Number
20633-84-5
Synonyms
  • Luteolin 7-Rutinoside
  • Luteolin 7-β-Rutinoside
  • Scolymoside
  • Skolimoside
Molecular Formula
C27H30O15
Formula Weight
594.5
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble
SMILES
O=C1C2=C(O)C=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)C=C2OC(C5=CC(O)=C(C=C5)O)=C1
InChi Code
InChI=1S/C27H30O15/c1-9-20(32)22(34)24(36)26(39-9)38-8-18-21(33)23(35)25(37)27(42-18)40-11-5-14(30)19-15(31)7-16(41-17(19)6-11)10-2-3-12(28)13(29)4-10/h2-7,9,18,20-30,32-37H,8H2,1H3/t9-,18+,20-,21+,22+,23-,24+,25+,26+,27+/m0/s1
InChi Key
MGYBYJXAXUBTQF-FOBVWLSUSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $83

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    5 mg

    $269

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    10 mg

    $495

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    25 mg

    $1,032

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    Product Description

    Luteolin 7-O-rutinoside is a polyketide-derived flavonoid glycoside that has been found in V. bugulifolium and has diverse biological activities.1,2,3 It scavenges DPPH (Item No. 14805) radicals in a cell-free assay when used at concentrations ranging from 1 to 50 µM.2 Luteolin 7-O-rutinoside is active against B. subtilis, S. aureus, A. tumefaciens, M. luteus, E. coli, and P. aeruginosa (MICs = 100-200 µg/ml).3 It is also active against C. albicans, S. cerevisiae, and C. lusitaniae (MICs = 100, 200, and 50 µg/ml, respectively). Luteolin 7-O-rutinoside (57.6 µg/animal) decreases hepatic and renal injury and increases survival in a mouse model of polyphosphate-induced lethal endotoxemia.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fraga, C.G. Plant Phenolics and Human Health: Biochemistry, Nutrition and Pharmacology. The Wiley-Iubmb series on biochemistry and molecular biology (2010).

    2. Wang, W., Simon, J.E., Aviles, I.F., et al. Analysis of antioxidative phenolic compounds in artichoke (Cynara scolymus L.). J. Agric. Food Chem. 51(3), 601-608 (2003).

    3. Zhu, X., Zhang, H., and Lo, R. Phenolic compounds from the leaf extract of artichoke (Cynara scolymus L.) and their antimicrobial activities. J. Agric. Food Chem. 52(25), 7272-7278 (2004).

    4. Lee, I.-C., and Bae, J.-S. Anti-inflammatory effects of vicenin-2 and scolymoside on polyphosphate-mediated vascular inflammatory responses. Inflamm. Res. 65(3), 203-212 (2016).