A xanthone scaffold
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Xanthone

Item No. 34098

Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9H-xanthen-9-one
CAS Number
90-47-1
Synonyms
  • NSC 14978
  • 9-oxo Xanthone
  • 9-Xanthone
Molecular Formula
C13H8O2
Formula Weight
196.2
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS (pH 7.2) (1:3): 0.25 mg/mlDMSO: 1 mg/mlEthanol: 1 mg/ml
λmax
233, 238 nm
SMILES
O=C1C2=CC=CC=C2OC3=CC=CC=C31
InChi Code
InChI=1S/C13H8O2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H
InChi Key
JNELGWHKGNBSMD-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    25 g

    $70

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    Product Description

    Xanthone is a polyketide synthase-derived xanthone that has been found in G. mangostana.1,2 It is the scaffold of several pharmacologically active compounds, including α-mangostin (Item No. 29108), garcinone D (Item No. 30906), and O-methyl sterigmatocystin (Item No. 22070).3 Xanthone inhibits monoamine oxidase A (MAO-A; IC50 = 0.84 µM).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rukachaisirikul, V., Satpradit, S., Klaiklay, S., et al. Polyketide anthraquinone, diphenyl ether, and xanthone derivatives from the soil fungus Penicillium sp. PSU-RSPG99. Tetrahedron 70(34), 5148-5152 (2014).

    2. Yoswathana, N., and Eshtiaghi, M.N. Optimization of subcritical ethanol extraction for xanthone from mangosteen pericarp. Int. J. Chem. Eng. Appl. 6(2), 115-119 (2015).

    3. El-Seedi, H.R., El-Barbary, M.A., El-Ghorab, D.M.H., et al. Recent insights into the biosynthesis and biological activities of natural xanthones. Curr. Med. Chem. 17(9), 854-901 (2010).