An oxidized form of biotin
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Biotin sulfone

Item No. 34144

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid, 5,5-dioxide
CAS Number
40720-05-6
Molecular Formula
C10H16N2O5S
Formula Weight
276.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: 1 mg/mlDMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml
SMILES
[H][C@@](C1)(NC(N2)=O)[C@@]2([H])[C@H](CCCCC(O)=O)S1(=O)=O
InChi Code
InChI=1S/C10H16N2O5S/c13-8(14)4-2-1-3-7-9-6(5-18(7,16)17)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
InChi Key
QPFQYMONYBAUCY-ZKWXMUAHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Cayman Chemical
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    Product Description

    Biotin sulfone is an oxidized form of biotin (Item No. 22582).1 It binds to avidin with a binding ratio of 0.332 compared with biotin.2 Biotin sulfone has been used to immobilize oligosaccharides on avidin-coated surfaces for the detection of anti-C. albicans antibodies.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Collot, M., Sendid, B., Fievez, A., et al. Biotin sulfone as a new tool for synthetic oligosaccharide immobilization: Application to multiple analysis profiling and surface plasmonic analysis of anti-Candida albicans antibody reactivity against α and β (1→2) oligomannosides. J. Med. Chem. 51(19), 6201-6210 (2008).

    2. Zempleni, J., and Mock, D.M. Advanced analysis of biotin metabolites in body fluids allows a more accurate measurement of biotin bioavailability and metabolism in humans. J. Nutr. 129(2S Suppl), 494S-497S (1999).