An amino acid
Related Products
Enantiomer(s)
23703L-Arginine (hydrochloride)
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D-Arginine

Item No. 34194

Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
157-06-2
Synonyms
  • (R)-Arginine
Molecular Formula
C6H14N4O2
Formula Weight
174.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
N=C(N)NCCC[C@@H](N)C(O)=O
InChi Code
InChI=1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m1/s1
InChi Key
ODKSFYDXXFIFQN-SCSAIBSYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 g

    $36

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    5 g

    $95

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    10 g

    $153

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    Product Description

    D-Arginine is an amino acid and the dextrorotary isomer of the conditionally essential amino acid L-arginine (Item No. 23703).1 It has been found in mouse brain.2 Unlike L-arginine, it is not a substrate for nitric oxide synthase and has been used as a negative control for the production of nitric oxide (NO) in isolated perfused rabbit aorta.3 D-Arginine inhibits the antinociceptive activity of L-arginine in a mouse model of carrageenan-induced pain when administered at a dose of 1,000 mg/kg.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Grishin, D.V., Zhdanov, D.D., Pokrovskaya, M.V., et al. D-amino acids in nature, agriculture and biomedicine. All Life 13(1), 11-22 (2020).

    2. Du, S., Wang, Y., Weatherly, C.A., et al. Variations of L- and D-amino acid levels in the brain of wild-type and mutant mice lacking D-amino acid oxidase activity. Anal. Bioanal. Chem. 410(12), 2971-2979 (2018).

    3. Rees, D.D., Palmer, R.M.J., Hodson, H.F., et al. A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation. Br. J. Pharmacol. 96(2), 418-424 (1989).

    4. Kawabata, A., Nishimura, Y., and Takagi, H. L-leucyl-L-arginine, naltrindole and D-arginine block antinociception elicited by L-arginine in mice with carrageenin-induced hyperalgesia. Br. J. Pharmacol. 107(4), 1096-1101 (1992).