An intermediate in L-arginine catabolism
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Parent Compound(s)
34194D-Arginine23703L-Arginine (hydrochloride)
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2-Oxoarginine

Item No. 9004337

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-[(aminoiminomethyl)amino]-2-oxo-pentanoic acid
CAS Number
3715-10-4
Synonyms
  • α-keto Arginine
  • α-keto-δ-Guanidinovaleric Acid
Molecular Formula
C6H11N3O3
Formula Weight
173.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: Slightly soluble: 0.1-1 mg/mlWater: Sparingly soluble: 1-10 mg/ml
SMILES
O=C(C(CCCNC(N)=N)=O)O
InChi Code
InChI=1S/C6H11N3O3/c7-6(8)9-3-1-2-4(10)5(11)12/h1-3H2,(H,11,12)(H4,7,8,9)
InChi Key
ARBHXJXXVVHMET-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $175

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    5 mg

    $525

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    10 mg

    $875

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    25 mg

    $1,750

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    Product Description

    2-Oxoarginine is an intermediate in the catabolism of the amino acid L-arginine (Item No. 23703).1 It is formed from L-arginine by deamination.2,3 2-Oxoarginine (10 mM) inhibits GABA- or glycine-induced chloride currents in primary dissociated mouse spinal cord neurons.3 Topical application of 2-oxoarginine to the sensory motor cortex induces epileptiform discharges in rabbits.4 Serum levels of 2-oxoarginine are increased in patients with argininemia and decreased in patients with glioma.1,5 SNPs in the gene encoding alanine-glyoxylate aminotransferase 2 (AGXT2) are associated with changes in serum levels of 2-oxoarginine.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

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