A fructooligosaccharide with prebiotic and antidiabetic activities
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1-Kestose

Item No. 34346

Technical Information
Formal Name
O-β-D-fructofuranosyl-(2→1)-β-D-fructofuranosyl α-D-glucopyranoside
CAS Number
470-69-9
Molecular Formula
C18H32O16
Formula Weight
Purity
≥95%
A solid
PBS (pH 7.2): 5 mg/ml
SMILES
OC[C@H]([C@H]([C@@H]1O)O)O[C@@]1(CO[C@@]2(CO)[C@@H](O)[C@H](O)[C@@H](CO)O2)O[C@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO
InChi Code
InChI=1S/C18H32O16/c19-1-6-9(23)12(26)13(27)16(31-6)34-18(15(29)11(25)8(3-21)33-18)5-30-17(4-22)14(28)10(24)7(2-20)32-17/h6-16,19-29H,1-5H2/t6-,7-,8-,9-,10-,11-,12+,13-,14+,15+,16-,17-,18+/m1/s1
InChi Key
VAWYEUIPHLMNNF-OESPXIITSA-N
Origin
Natural/Source unknown
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    1-Kestose is a fructooligosaccharide that has been found in onions and has prebiotic and antidiabetic activities.1,2,3 It increases levels of the beneficial bacterium B. longum in diluted adult human fecal samples when added to culture broth at a concentration of 0.5% w/v.3 Dietary supplementation with 1-kestose increases the proportion of cecal Anaerostipes and Bifidobacterium content, improves glucose tolerance, and prevents the development of type 2 diabetes in Otsuka Long-Evans Tokushima Fatty (OLETF) rats.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tochio, T., Kadota, Y., Tanaka, T., et al1-Kestose, the smallest fructooligosaccharide component, which efficiently stimulates Faecalibacterium prausnitzii as well as bifidobacteria in humans. Foods 7(9), 140 (2018).

    2. Watanabe, A., Kadota, Y., Kamio, R., et al1-Kestose supplementation mitigates the progressive deterioration of glucose metabolism in type 2 diabetes OLETF rats. Sci. Rep. 10(1), 15674 (2020).

    3. Endo, A., Hirano, K., Ose, R., et alImpact of kestose supplementation on the healthy adult microbiota in in vitro fecal batch cultures. Anaerobe 61, 102076 (2020).