A flavonoid glycoside with diverse biological activities
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Epimedin C

Item No. 34375

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-[[6-deoxy-2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-mannopyranosyl]oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
CAS Number
110642-44-9
Synonyms
  • Baohuoside VI
Molecular Formula
C39H50O19
Formula Weight
822.8
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
272 nm
SMILES
C/C(C)=C\CC1=C2C(C(C(O[C@H]3[C@@H]([C@@H]([C@H]([C@@H](O3)C)O)O)O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)=C(C5=CC=C(C=C5)OC)O2)=O)=C(C=C1O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO)O
InChi Code
InChI=1S/C39H50O19/c1-14(2)6-11-19-21(54-38-32(50)29(47)26(44)22(13-40)55-38)12-20(41)23-27(45)35(33(56-34(19)23)17-7-9-18(51-5)10-8-17)57-39-36(30(48)25(43)16(4)53-39)58-37-31(49)28(46)24(42)15(3)52-37/h6-10,12,15-16,22,24-26,28-32,36-44,46-50H,11,13H2,1-5H3/t15-,16-,22+,24-,25-,26+,28+,29-,30+,31+,32+,36+,37-,38+,39-/m0/s1
InChi Key
ULZLIYVOYYQJRO-JIYCBSMMSA-N
Origin
Plant/Epimedii folium
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $90

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    10 mg

    $142

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    25 mg

    $306

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    50 mg

    $479

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    Product Description

    Epimedin C is a flavonoid glycoside that has been found in E. koreanum and has diverse biological activities.1,2,3 It scavenges DPPH (Item No. 14805) radicals in a cell-free assay (IC50 = 142 µM).1 Epimedin B increases proliferation of UMR-106 osteoblasts by 30.4 and 41.6% when used at concentrations of 0.1 and 10 µM, respectively.2 It inhibits ear edema induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice (ED50 = 192 nmol/ear).3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kim, E.S., Kim, M.K., Kang, H.K., et al. Flavonol glycosides with antioxidant activity from the aerial parts of Epimedium koreanum nakai. Nat. Prod. Sci. 14(4), 233-238 (2008).

    2. Meng, F.-H., Li, Y.-B., Xiong, A.-L., et al. Osteoblastic proliferative activity of Epimedium brevicornum maxim. Phytomedicine 12(3), 189-193 (2005).

    3. Yasukawa, K., Ko, S.-K., and Whang, W.-K. Inhibitory effects of the aerial parts of Epimedium koreanum on TPA-induced inflammation and tumour promotion in two-stage carcinogenesis in mouse skin. J. Pharm. Nutr. Sci. 6(2), 38-42 (2016).