A potential impurity found in commercial preparations of lacosamide
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Descarbonyl Lacosamide

Item No. 34380

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2R-amino-3-methoxy-N-(phenylmethyl)-propanamide
CAS Number
196601-69-1
Synonyms
  • DP-I
Molecular Formula
C11H16N2O2
Formula Weight
208.3
Purity
≥95%
Formulation (Request formulation change)
An oil
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
COC[C@@H](N)C(NCC1=CC=CC=C1)=O
InChi Code
InChI=1S/C11H16N2O2/c1-15-8-10(12)11(14)13-7-9-5-3-2-4-6-9/h2-6,10H,7-8,12H2,1H3,(H,13,14)/t10-/m1/s1
InChi Key
WPLANNRKFDHEKD-SNVBAGLBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $63

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    100 mg

    $118

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    250 mg

    $257

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    500 mg

    $392

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    Product Description

    Descarbonyl-lacosamide is a potential impurity found in commercial preparations of lacosamide (Item No. 10012592).1 It is a degradation product formed under acidic conditions.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Molleti, S., Rao, V., and Jayaveera, K.N. Stability indicating RP-UPLC method for the determination of lacosamide and its impurities in bulk drugs and its pharmaceutical dosage forms. Der Pharma Chemica 5(1), 81-89 (2013).

    2. Tiwari, R.N., and Bonde, C.G. Identification and characterization of degradation products of lacosamide by liquid-chromatography/time-of-flight mass spectrometric and multi-stage mass spectrometric analysis. J. Liq. Chromatogr. 37(14), 2046-2061 (2014).