Enantiomer of (±)9-HETE; RXRγ activator
Related Products
Enantiomer(s)
344109(S)-HETE
Isomer(s)
34400(±)9-HETE
Labeled Version(s)
90035579(R)-HETE-d8
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

9(R)-HETE

Item No. 34405

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9R-hydroxy-5Z,7E,11Z,14Z-eicosatetraenoic acid
CAS Number
107656-14-4
Synonyms
  • 9(R)-Hydroxyeicosatetraenoic Acid
Molecular Formula
C20H32O3
Formula Weight
320.5
Purity
≥98%
Formulation
A 100 µg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
0.1 M Na2CO3: 2 mg/mlDMF: MiscibleDMSO: MiscibleEthanol: MisciblePBS pH 7.2: 0.8 mg/ml
λmax
235 nm
SMILES
CCCCC/C=C\C/C=C\C[C@H](/C=C/C=C\CCCC(O)=O)O
InChi Code
InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-10-13-16-19(21)17-14-11-9-12-15-18-20(22)23/h6-7,9-11,13-14,17,19,21H,2-5,8,12,15-16,18H2,1H3,(H,22,23)/b7-6-,11-9-,13-10-,17-14+/t19-/m1/s1
InChi Key
KATOYYZUTNAWSA-AZFZJQGOSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    25 µg

    $161

    Add

    50 µg

    $306

    Add

    100 µg

    $578

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    9(R)-HETE is an enantiomer which makes up 50% of (±)9-HETE (Item No. 34400). At a concentration of 300 nM, 9(R)-HETE activates RXRγ-dependent transcription 1.5 fold relative to a control.1 Stereochemical assignment of the (R) enantiomer is based on comparison of chiral HPLC retention times to published results. 2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Eager, N.S., Brickell, P.M., Snell, C., et al. Structural and functional evidence for activation of a chick retinoid X receptor by eicosanoids. Proc. Biol. Sci. 250(1327), 63-69 (1992).

    2. Schneider, C., Yu, Z., Boeglin, W.E., et al. Enantiomeric separation of hydroxy and hydroperoxy eicosanoids by chiral column chromatography. Methods Enzymol. 433, 145-157 (2007).