An internal standard for the quantification of 9-HETE
Related Products
Enantiomer(s)
90035589(S)-HETE-d8
Isomer(s)
9002386(±)9-HETE-d8
Unlabeled Version(s)
344059(R)-HETE
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9(R)-HETE-d8

Item No. 9003557

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5Z,7E,9R,11Z,14Z)- 9-hydroxy-5,7,11,14-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid
CAS Number
2738376-72-0
Synonyms
  • 9(R)-Hydroxyeicosatetraenoic Acid-d8
Molecular Formula
C20H24D8O3
Formula Weight
328.5
Purity
≥99% deuterated forms (d1-d8)
Formulation
A 100 µg/ml solution in acetonitrile
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 50 mg/mlPBS (pH 7.2): 0.5 mg/ml
SMILES
O[C@@](C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCCC)([2H])/C([2H])=C/C([2H])=C([2H])\CCCC(O)=O
InChi Code
InChI=1S/C20H32O3/c1-2-3-4-5-6-7-8-10-13-16-19(21)17-14-11-9-12-15-18-20(22)23/h6-7,9-11,13-14,17,19,21H,2-5,8,12,15-16,18H2,1H3,(H,22,23)/b7-6-,11-9-,13-10-,17-14+/t19-/m1/s1/i6D,7D,9D,10D,11D,13D,17D,19D
InChi Key
KATOYYZUTNAWSA-VSRPQYITSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    25 µg

    $203

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    50 µg

    $382

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    Product Description

    9(R)-HETE-d8 is intended for use as an internal standard for the quantification of 9-HETE by GC- or LC-MS. (±)9-HETE is formed by lipid peroxidation of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607).1 9(S)-HETE and 9(R)-HETE are formed via oxidation of arachidonic acid by rat liver microsomal cytochrome P450 (CYP) in a non-stereoselective manner.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Powell, W.S., and Rokach, J. Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid. Biochim. Biophys. Acta 1851(4), 340-355 (2014).

    2. Capdevila, J., Yadagiri, P., Manna, S., et al. Absolute configuration of the hydroxyeicosatetraenoic acids (HETEs) formed during catalytic oxygenation of arachidonic acid by microsomal cytochrome P-450. Biochem. Biophys. Res. Commun. 141(3), 1007-1011 (1986).