An oxylipin
Related Products
Enantiomer(s)
3451011(S)-HETE
Isomer(s)
34500(±)11-HETE
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

11(R)-HETE

Item No. 34505

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
11R-hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic acid
CAS Number
73347-43-0
Synonyms
  • 11(R)-Hydroxyeicosatetraenoic Acid
Molecular Formula
C20H32O3
Formula Weight
320.5
Purity
≥98%
Formulation (Request formulation change)
A 100 µg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
0.1 M Na2CO3: 2 mg/mlDMF: MiscibleDMSO: MiscibleEthanol: MisciblePBS pH 7.2: 0.8 mg/ml
λmax
236 nm
SMILES
CCCCC/C=C\C=C\[C@H](O)C/C=C\C/C=C\CCCC(O)=O
InChi Code
InChI=1S/C20H32O3/c1-2-3-4-5-7-10-13-16-19(21)17-14-11-8-6-9-12-15-18-20(22)23/h6-7,9-11,13-14,16,19,21H,2-5,8,12,15,17-18H2,1H3,(H,22,23)/b9-6-,10-7-,14-11-,16-13+/t19-/m0/s1
InChi Key
GCZRCCHPLVMMJE-WXMXURGXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    25 µg

    $156

    Add

    50 µg

    $263

    Add

    100 µg

    $493

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    11(R)-HETE is an oxylipin produced by COX-1 and COX-2 from arachidonic acid or aspirin-acetylated COX-2-mediated oxidation of arachidonic acid.1,2 It is also produced by 11(R)-lipoxygenases in the freshwater hydra (H. vulgaris), where it is involved in tentacle regeneration, and in the sea urchin (S. purpuratus).3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Thuresson, E.D., Lakkides, K.M., and Smith, W.L. Different catalytically competent arrangements of arachidonic acid within the cyclooxygenase active site of prostaglandin endoperoxide H synthase-1 lead to the formation of different oxygenated products. The Journal of Biological Chemisty 275(12), 8501-8507 (2000).

    2. Xiao, G., Tsai, A.l., Palmer, G., et al. Analysis of hydroperoxide-induced tyrosyl radicals and lipoxygenase activity in aspirin-treated human prostaglandin H synthase-2. Biochemistry 36(7), 1836-1845 (1997).

    3. Hawkins, D.J., and Brash, A.R. Eggs of the sea urchin, Strongylocentrotus purpuratus, contain a prominent (11R) and (12R) lipoxygenase activity. The Journal of Biological Chemisty 262(16), 7629-7634 (1987).

    4. Di Marzo, V., Gianfrani, C., De Petrocellis, L., et al. Polyunsaturated-fatty-acid oxidation in Hydra: Regioselectivity, substrate-dependent enantioselectivity and possible biological role. Biochem. J. 300, 501-507 (1994).