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Explore additional resources to study natural toxins, pollutants including PFAS and 6-PPD-Q, and their biological effects.
ENVIRONMENTAL TOXICOLOGY TOOLS & SERVICESPendimethalin is a dinitroaniline herbicide.1 It controls johnsongrass and increases seed cotton yield when used at concentrations ranging from 0.56 to 1.12 kg/ha. Pendimethalin (25-500 µM) induces the production of reactive oxygen species (ROS) and genotoxicity in isolated human peripheral lymphocytes.2 In vivo, pendimethalin (62.5, 125, and 250 mg/kg) increases renal and hepatic protein carbonylation, lipid peroxidation, necrosis, leukocyte infiltration, and formation of pyknotic nuclei in rats.3 Formulations containing pendimethalin have been used in the control of annual grasses in agriculture.
WARNING This product is not for human or veterinary use.
1. Comparative toxicity of several dinitroaniline herbicides. Weed Sci. 26(1), 72-75 (1978).
2. In vitro genotoxicity assessment of dinitroaniline herbicides pendimethalin and trifluralin. Food Chem. Toxicol. 113, 90-98 (2018).
3. Pendimethalin-