An internal standard for the quantification of nitroso sarcosine
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N-Nitroso Sarcosine-d3

Item No. 34740

Technical Information
Formal Name
N-(methyl-d3)-N-nitrosoglycine
CAS Number
1189871-94-0
Synonyms
  • MCMN-d3
  • N-Methyl-N-(carboxymethyl)nitrosamine-d3
Molecular Formula
C3H3D3N2O3
Formula Weight
Purity
≥99% deuterated forms (d1-d3)
Formulation
A solid
Chloroform: solubleDMSO: sparingly solubleMethanol: slightly soluble
SMILES
OC(CN(C([2H])([2H])[2H])N=O)=O
InChi Code
InChI=1S/C3H6N2O3/c1-5(4-8)2-3(6)7/h2H2,1H3,(H,6,7)/i1D3
InChi Key
HJMPSKKJHVWPBK-FIBGUPNXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    N-Nitrososarcosine-d3 is intended for use as an internal standard for the quantification of nitrososarcosine by GC- or LC-MS. N-Nitroso sarcosine is a nitrosamine.1 It has been found in smoked and cured meats and tobacco smoke.2,3 Dietary administration of N-nitroso sarcosine (0.25%) induces tumors in mice and administration via the drinking water at doses of 100 or 200 mg/kg induces tumors in rats.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1.  IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans: Some N-nitroso compounds. (1978).

    2. Herrmann, S., Duedahl-Olesen, L., and Granby, K. Occurrence of volatile and non-volatile N-nitrosamines in processed meat products and the role of heat treatment. Food Control 48, 163-169 (2015).

    3.  Report on carcinogens, fourteenth edition. (2016).