An NK1 receptor antagonist
Related Products
Alternative(s)
45625Maropitant (citrate)
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Maropitant

Item No. 34816

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2S,3S)-N-[[5-(1,1-dimethylethyl)-2-methoxyphenyl]methyl]-2-(diphenylmethyl)-1-azabicyclo[2.2.2]octan-3-amine
CAS Number
147116-67-4
Synonyms
  • CJ-11,972
Molecular Formula
C32H40N2O
Formula Weight
468.7
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
λmax
277 nm
SMILES
COC(C=CC(C(C)(C)C)=C1)=C1CN[C@@H](C2CCN3CC2)[C@@H]3C(C4=CC=CC=C4)C5=CC=CC=C5
InChi Code
InChI=1S/C32H40N2O/c1-32(2,3)27-15-16-28(35-4)26(21-27)22-33-30-25-17-19-34(20-18-25)31(30)29(23-11-7-5-8-12-23)24-13-9-6-10-14-24/h5-16,21,25,29-31,33H,17-20,22H2,1-4H3/t30-,31-/m0/s1
InChi Key
OMPCVMLFFSQFIX-CONSDPRKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $39

    Add

    5 mg

    $106

    Add

    10 mg

    $193

    Add

    25 mg

    $434

    Add
    Product Description

    Maropitant is an neurokinin-1 (NK1) receptor antagonist.1,2 It reduces motion sickness- or doxorubicin-induced emesis in dogs. Formulations containing maropitant have been used as antiemetics in dogs.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Benchaoui, H.A., Siedek, E.M., De La Puente-Redondo, V.A., et al. Efficacy of maropitant for preventing vomiting associated with motion sickness in dogs. Vet Rec. 161(13), 444-447 (2007).

    2. Rau, S.E., Barber, L.G., and Burgess, K.E. Efficacy of maropitant in the prevention of delayed vomiting associated with administration of doxorubicin to dogs. J. Vet. Intern. Med. 24(6), 1452-1457 (2021).