A methyl ester form of L-cysteine
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Mecysteine (hydrochloride)

Item No. 34847

Technical Information
Formal Name
L-cysteine, methyl ester, monohydrochloride
CAS Number
18598-63-5
Synonyms
  • NSC 161611
Molecular Formula
C4H9NO2S • HCl
Formula Weight
Purity
≥95%
A solid
DMF: 5 mg/mlDMSO: 15 mg/mlEthanol: 1 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
COC([C@@H](N)CS)=O.Cl
InChi Code
InChI=1S/C4H9NO2S.ClH/c1-7-4(6)3(5)2-8;/h3,8H,2,5H2,1H3;1H/t3-;/m0./s1
InChi Key
WHOHXJZQBJXAKL-DFWYDOINSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Mecysteine is a methyl ester form of the conditionally essential amino acid L-cysteine (Item No. 33309). It increases the output of respiratory tract fluid in anesthetized dogs when administered at doses of 30 and 100 mg/kg.1 Mecysteine has also been used in the synthesis of free fatty acid receptor 2 (FFAR2/GPR43) agonists.2 Formulations containing mecysteine have been used in the treatment of chronic obstructive pulmonary disease (COPD) and chronic bronchitis.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yanaura, S., Takeda, H., and Misawa, M. Behavior of mucus glycoproteins of tracheal secretory cells following L-cysteine methyl ester treatment. J. Pharmacobiodyn 5(8), 603-610 (1982).

    2. Hansen, A.H., Sergeev, E., Bolognini, D., et alDiscovery of a potent thiazolidine free fatty acid receptor 2 agonist with favorable pharmacokinetic properties. J. Med. Chem. 61(21), 9534-9550 (2018).