A conditionally essential amino acid
Related Products
Isomer(s)
41968DL-Cysteine
Labeled Version(s)
34838L-Cysteine-15N-d3
Pro-drug Form(s)
10006326Procysteine
Technical Support & Resources

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L-Cysteine

Item No. 33309

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
52-90-4
Synonyms
  • L-Cys
  • L-(+)-Cysteine
  • (R)-Cysteine
  • NSC 8746
Molecular Formula
C3H7NO2S
Formula Weight
121.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 20 mg/mlWater: 20 mg/ml
SMILES
OC([C@@H](N)CS)=O
InChi Code
InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
InChi Key
XUJNEKJLAYXESH-REOHCLBHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    50 g

    $36

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    100 g

    $63

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    250 g

    $135

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    500 g

    $253

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    Cayman Chemical
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    OBESITY RESEARCH SOLUTIONS
    Product Description

    L-Cysteine is a conditionally essential amino acid.1,2 It is produced from L-methionine through the transsulfuration pathway.1 L-Cysteine can also be derived from dietary sources and protein turnover. It is a precursor in the biosynthesis of the intracellular antioxidant glutathione (GSH; Item No. 10007461). L-Cysteine supplementation increases GSH levels as well as decreases oxidative stress and pro-inflammatory cytokine levels in various rat and porcine disease models, including type 2 diabetes, aging, and inflammatory bowel disease (IBD). It is also an excitotoxin, inducing neuronal damage by overactivation of NMDA receptors.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yin, J., Ren, W., Yang, G., et al. L-Cysteine metabolism and its nutritional implications. Mol. Nutr. Food Res. 60(1), 134-146 (2016).

    2. Janáky, R., Varga, V., Hermann, A., et al. Mechanisms of L-cysteine neurotoxicity. Neurochem. Res. 25(9-10), 1397-1405 (2000).