An intermediate in the synthesis of olmesartan medoxomil
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Tritylolmesartan Medoxomil

Item No. 34854

Technical Information
Formal Name
4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2′-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
CAS Number
144690-92-6
Molecular Formula
C48H44N6O6
Formula Weight
Purity
≥98%
A solid
DMF: 1 mg/mlDMSO: 1 mg/ml
SMILES
O=C(OCC1=C(C)OC(O1)=O)C2=C(C(C)(O)C)N=C(CCC)N2CC3=CC=C(C4=C(C5=NN=NN5C(C6=CC=CC=C6)(C7=CC=CC=C7)C8=CC=CC=C8)C=CC=C4)C=C3
InChi Code
InChI=1S/C48H44N6O6/c1-5-17-41-49-43(47(3,4)57)42(45(55)58-31-40-32(2)59-46(56)60-40)53(41)30-33-26-28-34(29-27-33)38-24-15-16-25-39(38)44-50-51-52-54(44)48(35-18-9-6-10-19-35,36-20-11-7-12-21-36)37-22-13-8-14-23-37/h6-16,18-29,57H,5,17,30-31H2,1-4H3
InChi Key
IJOPLMOXIPGJIJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Tritylolmesartan medoxomil is an intermediate in the synthesis of olmesartan medoxomil (Item No. 11614), a prodrug form of the angiotensin II receptor 1 (AT1) antagonist olmesartan (Item No. 23412).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hanumantha Rao, B., Subramanyeswara Rao, I.V., Ravi Kanth, V., et alA competent and commercially viable process for the synthesis of the anti-hypertensive drug olmesartan medoxomil. Sci. Pharm. 83(3), 465-478 (2015).