A GSK3 inhibitor
Related Products
Isomer(s)
15578CHIR98014
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CHIR98024

Item No. 34872

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N6-[2-[[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]-3-nitro-2,6-pyridinediamine
CAS Number
556813-39-9
Synonyms
  • CT 98024
Molecular Formula
C20H17Cl2N9O2
Formula Weight
486.3
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: slightly solubleEthanol: slightly soluble
SMILES
NC1=NC(NCCNC2=NC=C(C3=NC=CN3)C(C4=C(Cl)C=C(Cl)C=C4)=N2)=CC=C1[N+]([O-])=O
InChi Code
InChI=1S/C20H17Cl2N9O2/c21-11-1-2-12(14(22)9-11)17-13(19-25-6-7-26-19)10-28-20(30-17)27-8-5-24-16-4-3-15(31(32)33)18(23)29-16/h1-4,6-7,9-10H,5,8H2,(H,25,26)(H3,23,24,29)(H,27,28,30)
InChi Key
NDFXSHIIGXVOKT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $49

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    5 mg

    $154

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    10 mg

    $283

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    25 mg

    $645

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    Product Description

    CHIR98024 is an inhibitor of glycogen synthase kinase 3 (GSK3; IC50 = 0.56 nM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wagman, A.S., Johnson, K.W., and Bussiere, D.E. Discovery and development of GSK3 inhibitors for the treatment of type 2 diabetes. Curr. Pharm. Des. 10(10), 1105-1137 (2004).