An Analytical Reference Standard
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

N-Pyrrolidino Isotonitazene (citrate)

Item No. 34909

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Isotonitazepine
  • Isotonitazepyne
Technical Information
Formal Name
2-(4-isopropoxybenzyl)-5-nitro-1-(2-(pyrrolidin-1-yl)ethyl)-1H-benzo[d]imidazole, 2-hydroxy-1,2,3-propanetricarboxylate
Molecular Formula
C23H28N4O3 • C6H8O7
Formula Weight
600.6
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
240 nm
SMILES
CC(C)[O]C1=CC=C(C=C1)CC2=[N]C3=CC([N+]([O-])=O)=CC=C3[N]2CCN4CCCC4.OC(CC(O)=O)(C(O)=O)CC(O)=O
InChi Code
InChI=1S/C23H28N4O3.C6H8O7/c1-17(2)30-20-8-5-18(6-9-20)15-23-24-21-16-19(27(28)29)7-10-22(21)26(23)14-13-25-11-3-4-12-25;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-10,16-17H,3-4,11-15H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
InChi Key
XZGLLCLVIOGQGU-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $91

    Add

    5 mg

    $406

    Add
    Cayman Chemical
    Cayman Spectral Library

    Our free, searchable, GC-MS spectral database contains 70eV EI mass spectral data of 2,000+ of Cayman’s forensic drug standards.

    DOWNLOAD THE DATABASE
    Product Description

    N-Pyrrolidino isotonitazene (Item No. 34909) is an analytical reference standard that is categorized as an opioid.1 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kozell, L.B., Eshleman, A.J., Wolfrum, K.M., et al. Pharmacology of newly identified nitazene variants reveals structural determinants of affinity, potency, selectivity for mu opioid receptors. Neuropharmacology 276, 110512 (2025).

    Product Citations

    Robinson, M.J., Chen, L., Thakur, A., et al. Coordinated subpocket engagement underlies nitazene potency at the μ‑opioid receptor. ACS Chem. Neurosci. (2026).

    Sapkota, R., Lomnicki, E.E., and Subedi, B. Nitazenes discharged during Super Bowl and Mardi Gras celebrations in New Orleans, USA. Environ. Sci. Tech. Lett. (2026).

    Truver, M.T., Roman, M., Gomonit, M.M., et al. Fatal intoxications with nitazenes: Postmortem findings, toxicology, and in vitro characterization at the μ-opioid receptor of six nitazene analogues. Arch. Toxicol. (2026).

    Leonard, A.C., Lenert-Mondou, C., Chayer, R., et al. Computational design of dynamic biosensors for emerging synthetic opioids. BioRxiv (2025).

    Kriikku, P., Pelander, A., Jylhä, A., et al. Post-mortem identification and toxicological findings of fluetonitazepyne and isotonitazepyne. Drug Test. Anal. 17(7), 1-6 (2025).

    Hardwick, E.K., and Davidson, J.T. Structural characterization of nitazene analogs using electrospray ionization-tandem mass spectrometry (ESI-MS/MS). Drug Test Anal. (2025).

    Kozell, L.B., Eshelman, A., J., Wolfrum, K.M., et al. Pharmacologic characterization of substituted nitazenes at μ, κ, and Δ opioid receptors suggests high potential for toxicity. J. Pharmacol. Exp. Ther. 389(2), 219-228 (2024).