An internal standard for the quantification of albendazole sulfone
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Unlabeled Version(s)
35445Albendazole sulfone
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Albendazole sulfone-d3

Item No. 35129

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[6-(propylsulfonyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl-d3 ester
CAS Number
1448345-60-5
Synonyms
  • ABZ-SO2-d3
  • ABZ-SOO-d3
Molecular Formula
C12H12D3N3O4S
Formula Weight
300.3
Purity
≥99% deuterated forms (d1-d3)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: slightlyEthanol: insolPBS (pH 7.2): insol
λmax
223 nm
SMILES
CCCS(=O)(C1=CC=C(N=C(N2)NC(OC([2H])([2H])[2H])=O)C2=C1)=O
InChi Code
InChI=1S/C12H15N3O4S/c1-3-6-20(17,18)8-4-5-9-10(7-8)14-11(13-9)15-12(16)19-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)/i2D3
InChi Key
CLSJYOLYMZNKJB-BMSJAHLVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Albendazole sulfone-d3 is intended for use as an internal standard for the quantification of albendazole sulfone (Item No. 35445) by GC- or LC-MS. Albendazole sulfone is an active metabolite of the benzimidazole anthelmintic albendazole (Item No. 23705).1,2 It inhibits spore formation of E. hellem, E. cuniculi, and E. intestinalis in vitro (IC90s = <0.0001, <0.001, and <0.1 µg/ml, respectively).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Baliharová, V., Velík, J., Fimanová, K., et al. Inhibitory effect of albendazole and its metabolites on cytochromes P450 activities in rat and mouflon in vitro. Pharmacol. Rep. 57, 97-106 (2005).

    2. Ridoux, O., and Drancourt, M. In vitro susceptibilities of the microsporidia Encephalitozoon cuniculi, Encephalitozoon hellem, and Encephalitozoon intestinalis to albendazole and its sulfoxide and sulfone metabolites. Antimicrob. Agents and Chemother. 42(12), 3301-3303 (1998).