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Quercetin 3-O-β-D-xylopyranoside is a flavonoid glycoside that has been found in N. candida and has diverse biological activities.1,2,3 It reduces malondialdehyde (MDA) levels in isolated rat brain when used at a concentration of 10 µg/ml.1 Quercetin 3-O-β-D-xylopyranoside (10, 50, and 100 µg/ml) reduces LPS- and cerulein-induced increases in reactive oxygen species (ROS) production and levels of GRP78, a marker of endoplasmic reticulum stress, in an AR42J rat pancreatic acinar cell model of pancreatitis.2 In vivo, quercetin 3-O-β-D-xylopyranoside (12.5, 25, and 50 mg/kg) decreases serum TNF-α and IL-6 levels, myocardial MDA levels, and myocardial fibrosis, as well as improves cardiac function, in a rat model of ischemic heart failure.3
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1. A new flavonol glycoside and activity of compounds from the flower of Nymphaea candida. J. Asian Nat. Prod. Res. 9(3-5), 333-338 (2007).
2. Quercetin 3-
3. Reynoutrin improves ischemic heart failure in rats via targeting S100A1. Front. Pharmacol. 12, 703962 (2021).